Phenylketonuria Some Current Problems

Phenylketonuria. Some current problems.

Some current obstetric and gynaecological problems.

It has never been right to practise obstetrics and gynaecology in a purely mechanistic style. Medical practitioners have always discussed and argued, often driven by their patients, both the ethical framework and the individual circumstantial detail of practice within this specialty. This chapter starts by discussing the place of ethics and minimum core values for practice. Their integration in...

Cepheids as Distance Indicators: Some Current Problems

A general review is given of the calibration of the Cepheid distance scale, with particular reference to its use in the determination of H0. Emphasis is placed on the advantage of using a galactic calibration of the Cepheid scale, rather than relying on an adopted distance to the LMC. It is then possible to use LMC data to test for possible metallicity effects on this scale.

Dietary intervention in the management of phenylketonuria: current perspectives

Phenylketonuria (PKU) is a well-described inborn error of amino acid metabolism that has been treated for >60 years. Enzyme deficiency causes accumulation of phenylalanine (Phe) and if left untreated will lead to profound and irreversible intellectual disability in most children. Traditionally, it has been managed with a low-Phe diet supplemented with a Phe-free protein substitute although newe...

Some Current Quantitative Problems in Corpus Linguistics and a Sketch of Some Solutions

This paper surveys a variety of methodological problems in current quantitative corpus linguistics. Some problems discussed are from corpus linguistics in general, such as the impact that dispersion, type frequencies/ entropies, and directionality (should) have on the computation of association measures as well as the impact that neglecting the sampling structure of a corpus can have on a stati...